"","lowest_category","freq"
"1"," Exosome [BR:ko",115
"2"," Transporters [BR:ko",109
"3"," Glycolysis / Gluconeogenesis ",102
"4"," Ribosome ",102
"5"," Ribosome [BR:ko",102
"6"," Pyruvate metabolism ",83
"7"," Methane metabolism ",64
"8"," Citrate cycle (TCA cycle) ",57
"9"," ABC transporters ",54
"10"," Two-component system ",53
"11"," Oxidative phosphorylation ",51
"12"," Chaperones and folding catalysts [BR:ko",50
"13"," Carbon fixation in photosynthetic organisms ",48
"14"," Messenger RNA biogenesis [BR:ko",47
"15"," Carbon fixation pathways in prokaryotes ",46
"16"," Glyoxylate and dicarboxylate metabolism ",44
"17"," Mitochondrial biogenesis [BR:ko",44
"18"," Purine metabolism ",44
"19"," RNA degradation ",42
"20"," Quorum sensing ",41
"21"," Amino sugar and nucleotide sugar metabolism ",39
"22"," Chromosome and associated proteins [BR:ko",39
"23"," Glucagon signaling pathway ",38
"24"," Pentose phosphate pathway ",37
"25"," Amino acid related enzymes [BR:ko",36
"26"," DNA repair and recombination proteins [BR:ko",36
"27"," Fructose and mannose metabolism ",33
"28"," Glycine, serine and threonine metabolism ",32
"29"," HIF-",30
"30"," Membrane trafficking [BR:ko",30
"31"," Peptidases and inhibitors [BR:ko",30
"32"," Central carbon metabolism in cancer ",29
"33"," Butanoate metabolism ",27
"34"," Fatty acid biosynthesis ",27
"35"," Secretion system [BR:ko",27
"36"," Galactose metabolism ",26
"37"," Longevity regulating pathway - worm ",26
"38"," Transfer RNA biogenesis [BR:ko",26
"39"," Cysteine and methionine metabolism ",25
"40"," Peroxisome ",25
"41"," Photosynthesis ",25
"42"," Photosynthesis proteins [BR:ko",25
"43"," Bacterial secretion system ",23
"44"," Lipid biosynthesis proteins [BR:ko",23
"45"," Biofilm formation - Escherichia coli ",22
"46"," DNA replication proteins [BR:ko",22
"47"," Propanoate metabolism ",22
"48"," Protein export ",22
"49"," Aminoacyl-tRNA biosynthesis ",21
"50"," AMPK signaling pathway ",21
"51"," Pyrimidine metabolism ",21
"52"," Alanine, aspartate and glutamate metabolism ",20
"53"," Biofilm formation - Vibrio cholerae ",20
"54"," Peptidoglycan biosynthesis and degradation proteins [BR:ko",20
"55"," Tryptophan metabolism ",20
"56"," Enzymes with EC numbers",19
"57"," Transcription machinery [BR:ko",18
"58"," beta-Lactam resistance ",17
"59"," Longevity regulating pathway - multiple species ",17
"60"," Peptidoglycan biosynthesis ",17
"61"," Translation factors [BR:ko",17
"62"," Function unknown",16
"63"," Starch and sucrose metabolism ",16
"64"," Tuberculosis ",16
"65"," Valine, leucine and isoleucine degradation ",16
"66"," Amyotrophic lateral sclerosis (ALS) ",15
"67"," Cell cycle - Caulobacter ",15
"68"," MAPK signaling pathway - plant ",15
"69"," Arginine biosynthesis ",14
"70"," Cationic antimicrobial peptide (CAMP) resistance ",14
"71"," Valine, leucine and isoleucine biosynthesis ",14
"72"," Drug metabolism - other enzymes ",13
"73"," PPAR signaling pathway ",13
"74"," Salmonella infection ",13
"75"," Biofilm formation - Pseudomonas aeruginosa ",12
"76"," Lipopolysaccharide biosynthesis proteins [BR:ko",12
"77"," Phosphotransferase system (PTS) ",12
"78"," Protein phosphatases and associated proteins [BR:ko",12
"79"," Ribosome biogenesis [BR:ko",12
"80"," Nitrogen metabolism ",11
"81"," Transcription factors [BR:ko",11
"82"," Adipocytokine signaling pathway ",10
"83"," Fatty acid degradation ",10
"84"," Ferroptosis ",10
"85"," FoxO signaling pathway ",10
"86"," Glutathione metabolism ",10
"87"," Human papillomavirus infection ",10
"88"," Longevity regulating pathway ",10
"89"," Lysine degradation ",10
"90"," MAPK signaling pathway - yeast ",10
"91"," Nicotinate and nicotinamide metabolism ",10
"92"," Thermogenesis ",10
"93"," Type II diabetes mellitus ",10
"94"," Viral carcinogenesis ",10
"95"," Antimicrobial resistance genes [BR:ko",9
"96"," GABAergic synapse ",9
"97"," Glutamatergic synapse ",9
"98"," Insulin signaling pathway ",9
"99"," Legionellosis ",9
"100"," Lipopolysaccharide biosynthesis ",9
"101"," Necroptosis ",9
"102"," RNA polymerase ",9
"103"," Structural proteins",9
"104"," Type I diabetes mellitus ",9
"105"," Alzheimer disease ",8
"106"," Biotin metabolism ",8
"107"," Cyanoamino acid metabolism ",8
"108"," Pantothenate and CoA biosynthesis ",8
"109"," Pathogenic Escherichia coli infection ",8
"110"," Plant-pathogen interaction ",8
"111"," Cytoskeleton proteins [BR:ko",7
"112"," Glycosyltransferases [BR:ko",7
"113"," Homologous recombination ",7
"114"," One carbon pool by folate ",7
"115"," Vitamin B",7
"116"," Antifolate resistance ",6
"117"," Cushing syndrome ",6
"118"," Glucosinolate biosynthesis ",6
"119"," Pathways in cancer ",6
"120"," Renal cell carcinoma ",6
"121"," DNA replication ",5
"122"," Energy metabolism",5
"123"," Fluid shear stress and atherosclerosis ",5
"124"," Huntington disease ",5
"125"," Inositol phosphate metabolism ",5
"126"," Mismatch repair ",5
"127"," NOD-like receptor signaling pathway ",5
"128"," Parkinson disease ",5
"129"," Prion diseases ",5
"130"," Prokaryotic defense system [BR:ko",5
"131"," Riboflavin metabolism ",5
"132"," Selenocompound metabolism ",5
"133"," Taurine and hypotaurine metabolism ",5
"134"," D-Alanine metabolism ",4
"135"," Folate biosynthesis ",4
"136"," Glycerophospholipid metabolism ",4
"137"," Insulin resistance ",4
"138"," Pentose and glucuronate interconversions ",4
"139"," Prodigiosin biosynthesis ",4
"140"," Vancomycin resistance ",4
"141"," Arabinogalactan biosynthesis - Mycobacterium ",3
"142"," Bacterial chemotaxis ",3
"143"," Bacterial motility proteins [BR:ko",3
"144"," Biosynthesis of ansamycins ",3
"145"," D-Glutamine and D-glutamate metabolism ",3
"146"," General function prediction only",3
"147"," Lysine biosynthesis ",3
"148"," Prolactin signaling pathway ",3
"149"," Signaling proteins",3
"150"," Two-component system [BR:ko",3
"151"," Apoptosis - fly ",2
"152"," Arginine and proline metabolism ",2
"153"," Biosynthesis of unsaturated fatty acids ",2
"154"," Biosynthesis of various secondary metabolites - part",2
"155"," Lipoic acid metabolism ",2
"156"," Monobactam biosynthesis ",2
"157"," Nitrotoluene degradation ",2
"158"," Others",2
"159"," Phosphatidylinositol signaling system ",2
"160"," Protein processing",2
"161"," Sulfur metabolism ",2
"162"," Thyroid hormone synthesis ",2
"163"," Cell growth",1
"164"," Cofactor metabolism",1
"165"," Glycan metabolism",1
"166"," Phenylalanine, tyrosine and tryptophan biosynthesis ",1
"167"," Porphyrin and chlorophyll metabolism ",1
"168"," Transcription",1
"169"," Transport",1
"170"," Ubiquinone and other terpenoid-quinone biosynthesis ",1
