Loading required package: S4Vectors
Loading required package: stats4
Loading required package: BiocGenerics
Loading required package: parallel

Attaching package: ‘BiocGenerics’

The following objects are masked from ‘package:parallel’:

    clusterApply, clusterApplyLB, clusterCall, clusterEvalQ,
    clusterExport, clusterMap, parApply, parCapply, parLapply,
    parLapplyLB, parRapply, parSapply, parSapplyLB

The following objects are masked from ‘package:stats’:

    IQR, mad, sd, var, xtabs

The following objects are masked from ‘package:base’:

    anyDuplicated, append, as.data.frame, basename, cbind, colnames,
    dirname, do.call, duplicated, eval, evalq, Filter, Find, get, grep,
    grepl, intersect, is.unsorted, lapply, Map, mapply, match, mget,
    order, paste, pmax, pmax.int, pmin, pmin.int, Position, rank,
    rbind, Reduce, rownames, sapply, setdiff, sort, table, tapply,
    union, unique, unsplit, which, which.max, which.min


Attaching package: ‘S4Vectors’

The following object is masked from ‘package:base’:

    expand.grid

Loading required package: IRanges
Loading required package: GenomicRanges
Loading required package: GenomeInfoDb
Loading required package: SummarizedExperiment
Loading required package: Biobase
Welcome to Bioconductor

    Vignettes contain introductory material; view with
    'browseVignettes()'. To cite Bioconductor, see
    'citation("Biobase")', and for packages 'citation("pkgname")'.

Loading required package: DelayedArray
Loading required package: matrixStats

Attaching package: ‘matrixStats’

The following objects are masked from ‘package:Biobase’:

    anyMissing, rowMedians

Loading required package: BiocParallel

Attaching package: ‘DelayedArray’

The following objects are masked from ‘package:matrixStats’:

    colMaxs, colMins, colRanges, rowMaxs, rowMins, rowRanges

The following objects are masked from ‘package:base’:

    aperm, apply, rowsum

Loading required package: ggplot2
Loading required package: ggrepel

Attaching package: ‘dplyr’

The following object is masked from ‘package:matrixStats’:

    count

The following object is masked from ‘package:Biobase’:

    combine

The following objects are masked from ‘package:GenomicRanges’:

    intersect, setdiff, union

The following object is masked from ‘package:GenomeInfoDb’:

    intersect

The following objects are masked from ‘package:IRanges’:

    collapse, desc, intersect, setdiff, slice, union

The following objects are masked from ‘package:S4Vectors’:

    first, intersect, rename, setdiff, setequal, union

The following objects are masked from ‘package:BiocGenerics’:

    combine, intersect, setdiff, union

The following objects are masked from ‘package:stats’:

    filter, lag

The following objects are masked from ‘package:base’:

    intersect, setdiff, setequal, union

------------------------------------------------------------------------------
You have loaded plyr after dplyr - this is likely to cause problems.
If you need functions from both plyr and dplyr, please load plyr first, then dplyr:
library(plyr); library(dplyr)
------------------------------------------------------------------------------

Attaching package: ‘plyr’

The following objects are masked from ‘package:dplyr’:

    arrange, count, desc, failwith, id, mutate, rename, summarise,
    summarize

The following object is masked from ‘package:matrixStats’:

    count

The following object is masked from ‘package:IRanges’:

    desc

The following object is masked from ‘package:S4Vectors’:

    rename

estimating size factors
estimating dispersions
gene-wise dispersion estimates
mean-dispersion relationship
final dispersion estimates
fitting model and testing
null device 
          1 
null device 
          1 
Warning message:
Column `id` joining factors with different levels, coercing to character vector 
Warning message:
Column `ko` joining factors with different levels, coercing to character vector 
Warning message:
Column `id` joining factor and character vector, coercing into character vector 
Error in -1/sigdownkegg[, 1] : non-numeric argument to binary operator
Execution halted